Cayenne pepper, derived from various Capsicum species, has been used by Native Americans for thousands of years as both a culinary spice and a medicinal herb (Gonzalez-Burgos et al., 2011). Its distinct hot and spicy flavor comes from capsaicin, the active compound responsible for its numerous health benefits. This blog explores the rich history and diverse applications of cayenne pepper, shedding light on its traditional uses as well as the scientific evidence supporting its effectiveness in