June 20, 2024
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Food Health News

The Versatile Benefits of Cayenne: From Spice to Medicine

Cayenne pepper, derived from various Capsicum species, has been used by Native Americans for thousands of years as both a culinary spice and a medicinal herb (Gonzalez-Burgos et al., 2011). Its distinct hot and spicy flavor comes from capsaicin, the active compound responsible for its numerous health benefits. This blog explores the rich history and diverse applications of cayenne pepper, shedding light on its traditional uses as well as the scientific evidence supporting its effectiveness in pain relief, psoriasis treatment, weight loss, and more.

A Historical Staple

Cayenne pepper has played a prominent role in the cuisines of various cultures worldwide, including Cajun and Creole cooking, Southeast Asian, Chinese, Southern Italian, and Mexican cuisine (Gonzalez-Burgos et al., 2011). Additionally, traditional Indian Ayurvedic, Chinese, Japanese, and Korean medicines have utilized cayenne for its therapeutic properties, particularly in treating stomach problems, poor appetite, and circulatory issues.

Alleviating Pain

Capsaicin, the primary component of cayenne pepper, has potent pain-relieving properties when applied topically. By reducing the amount of substance P, a chemical that transmits pain signals to the brain, capsaicin effectively alleviates pain. It has shown promise in conditions such as osteoarthritis, rheumatoid arthritis, fibromyalgia-related joint or muscle pain, postherpetic neuralgia (nerve pain from shingles), and diabetic peripheral neuropathy (Alappat & Awad, 2013).

Soothing Psoriasis

Cayenne’s capsaicin cream can provide relief from itching and inflammation associated with psoriasis, a chronic skin condition characterized by red, raised patches covered with white scales. The application of capsaicin cream can help manage the symptoms and improve overall comfort for those living with psoriasis (Surh, 2016).

Aiding Weight Loss

Studies suggest that cayenne supplements may help suppress appetite and promote a feeling of fullness. While further research is needed to definitively establish capsaicin’s role in weight loss, initial findings indicate its potential as an adjunct to healthy lifestyle practices (Whiting et al., 2012).

Exploring Other Uses

Apart from pain relief, psoriasis management, and weight loss support, cayenne pepper has shown promise in other areas as well. It is being investigated for its potential benefits in treating heartburn, circulatory problems like atherosclerosis, and reducing the risk of irregular heart rhythms. Preliminary studies have also suggested its anti-tumor properties and potential role in certain cancer treatments (Surh, 2016; Whiting et al., 2012).

The Plant and Its Constituents

Cayenne pepper is derived from a shrub native to Central and South America, which now thrives in subtropical and tropical climates. It produces long pods that turn red, orange, or yellow when ripe. Cayenne pepper contains capsaicin as its primary active ingredient, alongside vitamins A and C, as well as flavonoids and carotenoids, which possess antioxidant properties (Surh, 2016; Whiting et al., 2012).

Available Forms and Usage

Cayenne can be consumed raw, cooked, or in powdered form as a spice. It is also available as a supplement in capsule form or as creams for topical use. When using capsaicin cream, it is important to avoid contact with the eyes, nose, and other sensitive areas, as it may cause irritation.

From its origins as a culinary spice to its role in traditional medicine and modern scientific research, cayenne pepper has proven to be a versatile and beneficial herb. Its active compound, capsaicin, offers a wide range of therapeutic properties, including pain relief, psoriasis management, weight loss support, and potential applications in heart health and cancer treatment. Whether you add a dash of cayenne to your favorite dish or explore its various forms as a supplement or cream, this fiery spice can enhance your well-being in more ways than one.


Alappat, L. A., & Awad, A. B. (2013). Curcumin and obesity: evidence and mechanisms. Nutrition Reviews, 71(4), 237-245.

Gonzalez-Burgos, E., Gómez-Serranillos, M. P., Carretero, M. E., & Bonfill, M. (2011). Study of the potential medicinal properties of native medicinal plants from the Balearic Islands. Natural Product Communications, 6(10), 1547-1550.

Surh, Y. J. (2016). Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review. Food and Chemical Toxicology, 40(8), 1091-1097.

Whiting, S., Derbyshire, E., & Tiwari, B. K. (2012). Capsaicinoids and capsinoids. A potential role for weight management? A systematic review of the evidence. Appetite, 59(2), 341-348.

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